A Secret Weapon For https://www.ceesdekker.net
A Secret Weapon For https://www.ceesdekker.net
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Non-equilibrium folding of individual DNA molecules recaptured up to a thousand situations inside of a good point out nanopore
Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond clever style and design in 2005. (nl)
SMC complexes can pass Actual physical roadblocks larger than their ring measurement, indicating a nontopological mechanism for DNA loop extrusion
Duration Charge of personal carbon nanotubes by nanostructuring With all the scanning tunneling microscope
Example (one) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is demonstrated in grey, the rim of your pore is highlighted in purple, along with a 3D rendering of your motion with the DNA rod is displayed.
The rotors harness energy from the nanoscale drinking water and ion movement that is created by a static chemical or electrochemical probable gradient from the nanopore, which can be founded through a salt gradient or used voltage, respectively. These artificial nanoengines self-organize and run autonomously in physiological situations, suggesting ways to developing Vitality-transducing motors at nanoscale interfaces.
Quite cool, but that wasn’t genuinely where by my curiosity lay. I planned to pioneer And that i had the feeling which was now not feasible, since the most fascinating basic insights experienced now been uncovered. cees dekker But my area experienced made numerous enjoyable new applications to measure personal molecules. I made a decision which i needed to apply this to biology, to look at it from a Bodily standpoint.’
Tests pseudotopological and nontopological versions for SMC-pushed DNA loop extrusion versus roadblock-traversal experiments
Character Physics many thanks the nameless reviewers for their contribution to your peer assessment of this get the job done.
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2004, discovery of new physics in translocation of DNA as a result of nanopores; initially experimental examine of ions conduction in nanofluidic channels; first electrochemistry with particular person solitary-wall carbon nanotubes; STM detection and control of phonons in carbon nanotubes; first electrical docking of microtubules on kinesin-coated nanostructures; to start with biophysics characterization on the mechanical properties of double-stranded RNA; and initially single-molecule analyze of DNA translocation by a restriction-modification enzyme.